Monday 9 October 2017

Single-use Systems to Ensure Safety and Efficiency of Pharmaceutical Filtration Systems

The need for vaccines and drugs to treat high-risk diseases has created a vacuum of efficient filtration systems. Pharmaceutical filtration systems are used by major pharmaceuticals to produce drugs on a large scale.


Rising Need in Drug Discovery & Development


Pharmaceutical filtration is a vital step in drug manufacturing in major pharmaceuticals. It can aid companies by reducing production costs. Bioprocess filters can be applied to small and large batches of bioreactors. They can provide options for usage of cell media, desired operating temperature, and required scale of operation. 

The trend of customized medicines, development of drugs to target smaller patient pools, and need for local manufacturing are pushing the demand for these filtration systems. Single-use systems are being highly preferred by pharmaceutical companies to avoid chances of contamination.

The Next Big Thing in Filtration Systems 


Sartorium Stedim Biotech, one of the leaders in the biopharmaceutical industry, has launched an enhanced version of its Sartocon filtration system, embedded with a polyether sulfone membrane. It can be used in monoclonal antibody manufacturing, small-scale batches, and clinical trials.

Millipore Sigma, a division of Merck KGaA, has launched single-use filters and capsules to ensure efficiency among biopharmaceutical manufacturers. The M-shaped filters have increased capacity in plugging feed streams and enhancing reliability of single-use systems.

Market Overview


The worldwide pharmaceutical filtration market is expected to exceed USD 37 billion by 2025, according to Grand View Research, Inc. It is driven by expansion of the biopharmaceutical industry and need for advanced filters to produce vaccines on a large scale. Prevalence of chronic diseases such as rheumatic arthritis, heart disease, and cancer is also expected to spur demand over the forecast period (2014 – 2025).

Membrane filters accounted for a major market share in 2016 due to their varied applications. Single-use systems are anticipated to exhibit a significant growth rate during the forecast period on account of low production time and low contamination rate associated with these filters. The Asia Pacific market is anticipated to grow at a lucrative rate on account of lax regulations as well availability of a large genome pool. Notable market players include 3M, Merck KGaA, Parker Hannifin Corporation, and Danaher Corporation.

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